High Technology : Innovation + Job News

Concerns about money are raising the legislative roof at the federal level. Meanwhile, jobs and innovation are flowing out of the US and into China, India and the EU. The US biopharmaceutical industry is undergoing major changes. Hundreds of small and medium sized firms require intensive capital to conduct research. Major players in the industry, including Sanofi-Aventis,Merck, Pfizer and AstraZeneca, have cut more than 43,000 jobs nationwide as of September 2010. Health care reform adds more uncertainty to the industry at large.

Rather than attempt to allocate nonexistent federal money for life sciences research and development, Representatives Chakah Fattah, Allyson Schwartz, and Pat Meehan, along with Senator Robert Casey Jr., have a plan to provide money on a national level for the life sciences industry though tax incentives. On July 25, the bipartisan group introduced The Life Sciences Jobs and Investment Act of 2011 at the University City Science Center, a locus of life science research.

"This legislation is about inventing the future," says Casey. "In Pennsylvania, we don't wait for events to overtake us."

Southeastern Pennsylvania's political leaders have a vested interest in life sciences, according to Schwartz, who pointed to the concentration of teaching hospitals, medical research and life science entrepreneurs here.

"It's one of the aspects of the American economy where we are still leading, but we won't continue if we can't compete," said Meehan, who stressed that the bipartisan effort will have a much better chance of passing. Schwartz added, "It's not an easy time to get anything done in Washington."

The legislation, introduced on July 25, doubles the credit from 20 to 40 percent for the first $150 million of life sciences research and development. Also, to encourage domestic productivity, companies that bring foreign profits back to the United States will enjoy a reduced tax rate, as long as those funds that are used to hire domestic scientists and researchers and make new investments in American research and development.

Source: Robert Casey Jr., Allyson Schwartz, Pat Meehan, US Congress
Writer: Sue Spolan

There's something cool going on with air conditioning. OxiCool, Inc. a Philadelphia-based company, which has received $400,000 in investment from Ben Franklin Technology Partners of Southeastern Pennsylvania, including $250,000 announced from its Competitive Energy Consortia last month, recently received a patent for its environmentally friendly air-cooling technology.  OxiCool is working under a Joint Development Agreement with one of the three largest truck companies in the world, and is about to finish their second prototype.

The technology uses water as the main refrigerant and low-grade, recycled heat from exhaust waste and other green sources as the main energy source. There are no toxic components and zero direct emissions; virtually this technology is completely clean.

OxiCool initially developed this technology to be used in sleeper cabs in long-haul trucks. Often the only way for drivers to power their air-conditioning units while they aren't driving is to idle their engines, producing exhaust and wasting fuel and contributing massive amounts of greenhouse gases into the atmosphere. OxiCool's product eliminates the need to idle because the technology uses minimal amounts of electricity to operate. This development has the potential to save nearly 11 million tons of carbon dioxide annually, as well as a lot of grief for truck drivers in the more than 30 states that have introduced anti-idling legislation.

OxiCool's joint research and development agreement with the U.S. Navy and another with an unnamed large U.S. corporation comprise much of its work at present. The Philadelphia Industrial Development Corporation and private angel investors from across the country are other investors. OxiCool is in hiring mode, looking for "exceptional candidates."

Source: Emma Kaye, OxiCool
Writer: Nina Rosenberg

As America races to maintain standing in the global economy, industry clusters have been touted as a key strategy for technological innovation. While Silicon Valley and North Carolina's Research Triangle are held as bright spots where higher education meets high tech, few innovation clusters are successful. A recent column in the Washington Post dubbed government funded industry clusters "the modern day snake oil," doomed to fail.

At the third annual Regional Affinity Incubation Network (RAIN) meeting, held last week at the University City Science Center, David Finegold, Dean of Rutgers' School of Management and Labor Relations, responded. "A lot of efforts haven't panned out, but industry clusters are not without hope." He explained that early efforts were "real estate plays." What sets the tri-state region apart is the ability to build from that which is distinctive about this area, said Finegold, rather than starting from scratch and hoping that if it's built, innovation will come.

New Jersey, in particular, has nowhere to go but up, having ranked last in 2010 in U.S. job creation. While traditionally the state was a leader in biopharma and telecommunications, these industries made up a large-firm culture, and it's now time to build diverse networks, according to Finegold.

The University City District in Philadelphia is a 2.5 square mile powerhouse of commercial and institutional vitality, employing 70,000 people, according to UCD president Matthew Bergheiser. Forty percent of NIH funding in Pennsylvania is granted to projects within the boundaries of University City, and the Science Center has long been a fertile startup breeding ground that encourages organic growth, rather than superimposing ideas of innovation on an otherwise bereft area.

In Delaware, by contrast, plans are underway to convert Newark's former Chrysler assembly plant into an 250 acre innovation hub complete with living and working space, with an existing rail station to encourage commuters, and the potential to create collaboration across state lines, according to David Weir, PhD, Director of the Office of the Economic Innovation & Partnerships at the University of Delaware.

With a continued soft real estate market, Finegold offers that the way out of the recession is through leveraging human capabilities and university facilities. "We already have a great talent base here," said Finegold of efforts in Pennsylvania, New Jersey and Delaware, which he terms one of the most diverse regions on the planet.

RAIN is a regional network of over 40 research parks, incubators and support organizations located in the tri-state area.

Source: David Finegold, Matthew Bergheiser, David Weir, RAIN
Writer: Sue Spolan

PHOTO:

Former Chrysler Assembly Plant in Newark DE

In the game called World of Startup, the main characters are geeks and suits. PhillyMerge was created to help the two tribes meet on common ground, where developers and entrepreneurs can learn some slick moves from one another. It's a long standing and sometimes contentious relationship characterized by the blog Whartonite Seeks Code Monkey, in which MBAs are called to task for asking developers to work for peanuts.

The one day conference, held July 15, drew about 50 business types and coders to Huntsman Hall at the Wharton School of the University of Pennsylvania. Organized by Steve Rittler and Adam Tuttle, who met at the Philadelphia Cold Fusion User Group (CFUG), the event offered an even split of speakers. Chris Stanchak from TicketLeap told war stories about founding and growing the online event ticketing company, overcoming hiccups and navigating through three successive builds.

Attorney Frank Taney, who practices at Buchanan Ingersoll & Rooney, addressed legal issues confronting emerging businesses. Jim Caruso of the accounting firm Fesnak and Associates explained financial forecasts and projections, and helped one attendee understand why his spreadsheets were flawed.

Rittler and Tuttle said PhillyMerge ran like clockwork, with a running commentary on twitter and feedback boards. "People are really happy," said Rittler. "They like the flavor. It's different from what you usually see, where there's not a lot of crossover."

Total cost of the conference was estimated at $3000, and because Tuttle works at Wharton Learning Lab, space that would have doubled the cost was donated gratis. Sponsors included Adobe, Chariot Solutions and Duck Duck Go.

While Tuttle and Rittler did not ask this year's attendees if they played for the geek or suit side, they estimate it was about 70/30 in favor of techies. "That's a lesson learned," said Tuttle, who garnered a wealth of wisdom for planning and running next year's conference. Like a tenet heard often in entrepreneurial circles, PhillyMerge isn't built for exit. It's built for lifestyle.

Source: Steve Rittler, Adam Tuttle, PhillyMerge
Writer: Sue Spolan

Robert Cheetham, founder and CEO of Philadelphia-based geospatial analysis firm Azavea, is all about good growth. "We hire conservatively. We're not a venture capital funded company. We grow based on cash flow and the amount of business coming in, so there's not much margin for error."

His company is currently in the process of building staff. Some positions have recently been filled, while others are in the resume review stage, and still other positions are yet to be posted.

Azavea has built a strong reputation for merging geographic data with web and mobile software. Its high profile projects include the recently released PhillyTreeMap, which can easily be adapted to any city in the world and was funded by a research and development grant from the USDA; PhillyStormWater, to assist the Philadelphia Water Department's Green Stormwater Management Initiative, and a yet to be launched open source redistricting tool for implementation anywhere in America.

Azavea has just added several administrative and marketing assistants, a Graphic Information System (GIS) Analyst and a web designer. "We have grown every year we've been around," reflects Cheetham. "The last 2 years were relatively slow. Last year was 6 to 7 percent growth. The year before, nine percent. This year we're on track to grow 20 percent."

The secret of Azavea's growth is a mix of spending on business development and marketing through lean times, along with the lucky decision to hire a dedicated grant proposal writer just as the recession began. "We didn't necessarily anticipate the recession," says Cheetham, expanding Azavea nationally as well as internationally, with a recent job for the City of Toronto. "We get a fair amount of federal R&D work," says Cheetham, and while that's not the most profitable sector of the business, it's good for cash flow and pays for research that lays the groundwork for applications that can be adapted to any city or region in the world.

Azavea is always looking for great software engineers, a job sector that has remained fairly recession proof. In comparison, administrative job listings yield hundreds of resumes, and as a result, Azavea has developed a tool to select applicants. "We have crafted a questionnaire that requires job seekers to go to our website and look at the projects we do," says Cheetham.

Those who make it to the interview round have a much better take on Azavea's work and environment, and are able to explain exactly why Azavea is the right fit. It's almost like a college application, says Cheetham, who adds that he asks would-be employees where they heard about the job opening, allowing Azavea target the most effective places to advertise. Maybe there's a future app: Azavea Management Map?

Source: Robert Cheetham, Azavea
Writer: Sue Spolan

Days before longtime tenant BioNanomatrix announced its move to San Diego, the University City Science Center recently welcomed five new companies, and continues to be an incubator for both startups as well as international companies wishing to establish a U.S. base and national companies hoping to move into the Philadelphia market.

The new tenants include life science companies Longevity Biotech, Claremont, and Epitek, Inc.; investment firm Karlin Asset Management; and Parsortix, Inc. a French company that specializes in the transportation and medical equipment sectors.

Scott Shandler is co-founder of Longevity along with Dr. Sam Gellman of the University of Wisconsin. "Longevity develops market leading, novel therapeutics for both rare and widespread diseases," explains Shandler, who has a dual background in finance and biochemistry.

Longevity's primary product is the proprietary Hybridtide platform, developed at Gellman's academic lab in Wisconsin, enables the development of new therapies to treat a range of diseases including primary arterial hypertension, small cell lung cancer, type II diabetes and HIV, according to Shandler. Longevity currently has a contract with Fox Chase Cancer Center. "The exciting science in Dr. Gellman's labs together with the increasing lack of products within the Big Pharma pipelines led me to commercialize this line of work," says Shandler.

Claremont's sole employee is Blandine Chantepie, the U.S. director of sales and business development. Chantepie fell in love with Philadelphia in general and the University City incubator in particular, having already occupied space at SciCenter while working for Claremont parent company Ballina Capital group.

Claremont's two divisions have quite different client bases. Its medical device division manufactures a laser for dental use. "They have been selling around the world, and are strong in Europe and Korea," says Chantepie. Now the company wants to make inroads into the U.S market. Already past the hurdle of FDA approval, it's just a matter of setting up a sales and distribution network, which is already showing early success. Chantepie cites the proximity of Penn Dental School as a selling point for the company's location.

Calremont's train parts division looks to Amtrak and SEPTA for major contracts, and Chantepie says that Philadelphia's central spot along the heavily travelled Northeast Corridor is ideal. Many of Amtrak's corporate offices are right here in Philadelphia in the floors above 30th Street Station. Chantepie anticipates hiring employees within the next six to twelve months.

The remaining three companies moving into the SciCenter are early stage investor Karlin Asset Management, a Los Angeles based firm with $1 billion in equity capital; life sciences firm Epitek develops treatments for radiation exposure and methods of radiation prevention, and Parsortix is a particle separation company founded in 2006 that is developing applications for stem cells, oncology, pre-natal diagnostics and bacteria.

Source: Blandine Chantepie, Claremont; Scott Shandler, Longevity
Writer: Sue Spolan

"I was a Science Center squatter," says Han Cao, founder of life sciences startup Bionanomatrix, now valued at $40 million. It's success stories like these that inspired the new Quorum at the University City Science Center. Back when Cao was a struggling scientist, he occupied virtual office space at the SciCenter. But when rent money dried up, Cao camped out anywhere he could, hiding behind a column in the lobby or setting up shop by the coffee machine.

The Quorum is a well-appointed series of rooms that can be opened into one big space or divided into smaller areas. With a sweeping view of the city, SciCenter CEO Stephen Tang calls the space a clubhouse. "We acknowledge the universal need to meet people," says Tang, who feels that face time is an essential part of business success. With so many electronic ways to connect, meeting in person is harder when you don't know where to go.

Philadelphia's business and government leaders were present last Thursday to bless the grand opening of the 4,000 square foot Quorum, including Mayor Michael Nutter, Duane Morris attorney Richard Jaffe, who is the outgoing SciCenter Chairman of The Board, Craig Carnaroli, who replaces Jaffe in that role in addition to his day job as executive vice president of the University of Pennsylvania; Mel Baiada, founder of BaseCamp Business, and State Representative Jim Roebuck.

Upcoming events planned for the Quorum are designed to unite area business leaders with entrepreneurs; on June 20, Smart Talk: Adventures in Entrepreneurialism, Deloitte Fast 50 Secrets of Success features CEOs from some of the region's fastest growing companies giving advice to hopefuls who may one day be able to tell their own mutli-million dollar success stories.

Source: Han Cao, Bionanomatrix; Stephen Tang, University City Science Center
Writer: Sue Spolan

Philadelphia has made the cut, and is one of 10 finalists for the 2012 Code for America program. A national initiative that launched last year, Code for America links programmers with city government to create new avenues for civic participation. Philadelphia is a 2011 Code for America city, and Jeff Friedman, Manager of Civic Innovation and Participation for the City of Philadelphia, says Philly is all but assured a back to back nomination for the second year in a row.

Philadelphia's coding project is still in development, and you can get a sneak preview of the tool on June 15 at the Municipal Services Building. Friedman says the fellows began in earnest in January of this year with a month of orientation in San Francisco, returning east to do requirements gathering, meeting close to 200 people, and participating in a hackathon. The program is expected to roll out this fall.

But, you may ask, what does it do? "It helps people get projects done in and outside of government," explains Friedman, who uses as an example his own East Falls neighborhood. "Let's say I want to get a playground for my local park. I start a project with the Code for America tool. Now I am a known quantity and people can join my project. Once I have opened it up to the world, I find that there are actually 37 people who also want to work with me, and I can also locate another 17 people in the city who have been identified as experts in recreational development."

Friedman calls the initiative a revamped version of a public/private partnership that helps compress the life cycle of civic projects. "It's in line with a lot of the work we've been encouraged to do in this administration. We're using a new term, civic fusion, to explain this phase of using Internet tools for localized utility."

Source: Jeff Friedman, City of Philadelphia
Writer: Sue Spolan

One of the goals of the Philadelphia Navy Yard-based Greater Philadelphia Innovation Cluster (GPIC) is job creation. And they've got your jobs right here. GPIC, a consortium includes Pennsylvania State University, Philadelphia Industrial Development Corporation (PIDC), Ben Franklin Technology Partners of Southeastern PA (BFTP/SEP), the Delaware Valley Industrial Resource Center, and the Wharton Small Business Development Center, has five available positions spread out among these members.

"This is an early wave," says Christine Knapp, Manager of Public and Client Relations at GPIC, her own position falling under the auspices of Penn State. "These are jobs that are really conducting the work of GPIC."

The available positions are a Post-Doctoral Scholar, an Intellectual Property Associate, a Program Director, a Database Analyst, and an Administrative Assistant. Knapp runs down the details. There has not been as much response to the architectural engineering post-doc scholar, as it is a highly specialized position in which the candidate would be assisting in the research and development of building systems.

The Intellectual Property Associate does not need a law degree; rather, says Knapp, the BFTP/SEP based position would take the lead in the commercialization and deployment task area. "One concern is that intellectual property is correctly managed," says Knapp. "Our companies have sensitive proprietary information, and as they are discovering things and getting them to the marketplace, we need to make sure that people get credit."

The Program Director is specifically associated with the Small Business Development Center of The Wharton School at Penn. "Each of the members is required to have a full time GPIC staff member, and this would be their liaison," explains Knapp.

The Database analyst is actually two positions, both at BFTP/SEP. "We are doing a lot of data gathering," says Knapp. "We're researching building energy use, consumption and performance." The analyst would also draw on existing databases, and ultimately the reports would be sent to the Department of Energy. "We want to be sure that the data is getting integrated and all task areas have access," says Knapp.

Finally, the Administrative Assistant will be working closely with Knapp at the Navy Yard, and ideally should be someone who can handle not only clerical tasks but also logistics, planning events and outreach engagement work. "It would be someone who is interested in moving up and taking on more responsibility," says Knapp, who expects hundreds of resumes. The GPIC positions will remain posted until filled, which is expected to happen around mid-July, but each position has its own timeline.

Source: Christine Knapp, GPIC
Writer: Sue Spolan

Eternity just got a little longer and a lot more powerful, thanks to a new Android app. West Laurel Hill Cemetery in Bala Cynwyd has launched an interactive cemetery guide designed to run on the Samsung Galaxy tablet. It's a pilot program designed by WebCemeteries, and the first of its kind in the country. West Laurel Hill and its cross-river predecessor Laurel Hill have always been ahead of the times. Back in the 1800s, founder John Jay Smith envisioned a rural burial ground, away from the city. Before Laurel Hill, the only option for burial was in a churchyard. In 1836 and in 1869, Smith built havens for the heavenly in Laurel Hill and West Laurel Hill, creating verdant spaces that attracted families out for a Sunday picnic. There was even a train that stopped directly at West Laurel Hill for just such visits.

The idea of creating a non-denominational park setting for the dead caught on like wildfire in the 19th century. And then cemeteries pretty much remained the same. The great majority of memorial parks still do business on paper. West Laurel Hill has broken new ground in other ways, creating a scattering garden for loved ones' ashes, a green burial section, and a soon to be opened Jewish section. "We're proud of the fact that West Laurel Hill embraces new trends," says Deborah Cassidy, the cemetery's Marketing Manager. Working with WebCemeteries of Virginville, Berks County, on the mobile app, visitors can access photos, video, text and other information graveside. There is a built in GPS to keep you on track. Additionally, says Cassidy, the app will increase efficiency internally, allowing the office to go paperless.

There are a lot of famous Philadelphians buried at West Laurel Hill. So far, says Cassidy, about 25 of the cemetery's permanent residents are featured on the app. Videos were produced by Gillian Hurt of GH Video Communications, a Bala Cynwyd based production company. Preview some of Hurt's West Laurel Hill videos on architect Horace Trumbauer, hat magnate John B. Stetson, and Dr. John Thompson Dorrance of Campbell's Soup.

For now, visitors to the cemetery can check out one of six tablets running the app; Cassidy says plans are underway to release the smartphone tour as a paid app to the general public in the next six months.

Source: Deborah Cassidy, West Laurel Hill Cemetery
Writer: Sue Spolan

Flying Bytes is a recurring roundup of innovation and quick updates on the people and companies we're covering:

SEPTA launches TransitView
Back in January, we reported that SEPTA was weeks away from launching a real-time, system wide tracking program. The future is finally here. Like SEPTA's TrainView for regional rail, the new TransitView provides live updates on the whereabouts of buses and trolleys throughout the city. Also launched: SMS Transit Schedule Information, allowing customers to receive a text with the next four scheduled trips, and Schedules to Go, a mobile website function that provides information on the next ten scheduled trips.

Shah closes $72 million IPO with Universal Business Payment Solutions
Following a hot tip, we learned that Bipin Shah, creator of the MAC, was seeking $72 million for payments startup Universal Business Payment Solutions. On May 13, UPBS (NASDAQ: UBPSU) got its money. According to Shah's partner Peter Davidson, "we closed on 12 million shares at $6.00 per share. The underwriters have a 45 day option to cover any over-allotments, which they have not exercised to date." Investors include hedge fund magnate J. Kyle Bass, who purchased about 800,000 shares.

Philadelphia Printworks up, running, finding its market
The lovely ladies at the helm of Philadelphia Printworks are going full speed with their new T-shirt business. Co-founder April Pugh reports that most of PPW's customer base has come from custom work, particularly from local indie rock artists. PPW loves its rockers right back and offers a band discount. Pugh says she and partner Ruth Paloma Rivera-Perez are now seeking partnerships with retail outlets and will be selling at upcoming summer festivals.

Specticast expands with EuroArts partnership
Digital entertainment distribution company Specticast continues to widen its reach. The company, which we originally profiled back in April, announced an exclusive partnership with EuroArts, bringing live and pre-recorded events from Berlin's Philharmonie, The Sheldonian Theater at Oxford University, and Madrid's Teatro Real, according to Mark Rupp, SpectiCast president.

Source: Andrew Busch, SEPTA; Peter Davidson, UBPS; April Pugh, PPW; Mark Rupp, Specticast
Writer: Sue Spolan

A very common element forms the basis for a breakthrough portable power source. Philadelphia's AlumiFuel Power Inc. has developed a portable power system based on the chemical reaction of aluminum powder and water, according to CEO David Cade.

Using proprietary technology to strip the oxides from aluminum particles, the hydrogen generated is five times the density of a lithium battery, says Cade. "Our particular focus is portable, mobile and remote applications. We do on site, on demand power." The Alumifuel container is prefilled with aluminum powder. "The canister can be stored for years," says Cade. "You don't get hydrogen until you get water." A perfect application of the new fuel source is for the U.S Navy, which will pilot the hydrogen battery to propel unmanned undersea vehicles. Alumifuel is partnering with Ingenium Technologies for the project.

Cade is also excited by PBIS-1000, Alumifuel-powered weather balloons created in partnership with Kaymont Weather Balloons.

While Alumifuel is still "under the radar screen," and taking on a 100 year-old battery industry, Cade looks to continuing partnerships with major players like Ingenium and Kaymont to get the word out about a power source that provides 5-10 times the power of a lithium battery, is in no danger of exploding, and does not rely upon overseas oil and gas supplies.

"No one has ever commercialized this technology," says Cade. "There have been patents for years, but they have all been laboratory curiosities." The early stage company, based at the University City Science Center, is currently valued at under $100,000 and is in late development, early production stage. Cade says his partner, Henry Fong, is currently out raising capital, and if Alumifuel is awarded government grants, Cade and Fong's company could see serious growth.

Source: David Cade, Alumifuel Power Inc.
Writer: Sue Spolan

On the banks of the Delaware River, a green data center is set to rise from the remains of an old steel mill. David Crocker, CEO of Steel Orca LLC, says that while demand for data centers is growing at about 18 percent per year, supply is growing at only 5 percent every year. With many older data centers becoming obsolete in the face of new technology and increased power requirements, Steel Orca's goal is to build the greenest data center in the world, powered entirely by renewable energy sources. "Three to five percent of all energy generated in the United States goes into data centers. You can appreciate that data centers have a responsibility to be as efficient as possible," says Crocker.

As power density increases, so do cooling requirements. Steel Orca's planned center near Fairless Hills in Bucks County will require 100 megawatts of power, with an ultimate goal of 300,000 square feet of 'white space,' the term coined to describe the area where the servers are located, with a total footprint of 730,000 square feet.

The data center is in now the planning stage. HP has signed on to lead the design and construction team, with help from GE, Gilbane Construction and Villanova University Professor Alphonso Ortega. Ideas in the works include a triple failsafe power system, river water as a cooling mechanism, solar panels and and wind turbine generation.

Crocker terms the future center "a source of technological renaissance in the Delaware Valley," eventually creating 1,100 jobs in Bucks County. Steel Orca has completed a first round of funding with more than 50 investors, and Crocker projects that the first phase of the center, with at least 50,000 square feet of white space, will go online in the second quarter of 2012.

Source: David Crocker, Steel Orca
Writer: Sue Spolan

Maybe you take a couple of different prescription medications. If you don't now, chances are that as you get older, you will. And the interaction between drugs can be a wild card. That's where Absorption Systems rides in like a pharmaceutical cavalry. Based in Exton, the privately held company is a pioneer in the field of pharmacokinetics. As CEO Patrick Dentinger explains, there are two areas of preclinical drug research: pharmacodynamics, or what a drug does to your body, and pharmacokinetics, which is what your body does to the drug. The latter is Absorption Systems' specialty. "The FDA has gotten tougher in trying to understand what a drug does when it hits your body," says Dentinger. The company researches the path that singular and multiple meds take through the body.

In a series of buildings filled with lab coated technicians and millions of dollars of equipment, Absorption Systems is big pharma's first stop on the way to developing a drug that will eventually go to market, perhaps a decade down the line. Many compounds don't even make it out of the research phase, and Dentinger reports that most of the time, pharmaceutical clients do not share the purpose of the proposed drug, just the chemical compound.

Once a compound is submitted to Absorption System's lab, it goes through rigorous testing involving human tissue to simulate the interaction. Absorption Systems grows intestine, liver and skin cells, and out of a scene from the classic Woody Allen film Sleeper, the company has even used human noses (harvested from cadavers) to measure the way a molecule does or doesn't get into a body.

"The industry has changed in general," explains Dentinger, who describes formerly high walls of privacy surrounding pharmaceutical research crumbling in recent years with outsourcing to biotech startups and contract research organizations (CROs) like Absorption.

While Dentinger, whose sole partner is Ismael Hidalgo, does not disclose details of the privately held company's revenue, Absorption Systems is certainly growing, with over 200 customers and 115 employees, a satellite lab in San Diego and direct interaction with the FDA. The company hopes its future proprietary data collection technology can revolutionize the way all scientific research is documented and potentially create a spinoff company.

Source: Patrick Dentinger, Absorption Systems
Writer: Sue Spolan